Brain Death - 3rd Edition by Wijdicks

Oxford University Press has just published the 3rd edition of Brain Death by the leading expert on brain death, Eelco F.M. Wijdicks.






Brain Death provides a practical, comprehensive, clinical resource for practitioners seeing patients with acute catastrophic neurologic disorders evolving to brain death and all its ramifications. The clinical diagnosis of brain death has tremendous implications: its main purpose is to bring closure, but it often results in organ and tissue transplantation questions which need to be addressed.





This third edition introduces new research in the intensive care unit, newly unearthed historical data on important US-UK differences, a thorough discussion of US guidelines and how it is used in hospital practices, and compares guidelines used elsewhere in the world. In this incisive work, the many complexities of diagnosis and management of brain death are examined but it also illuminates cultural beliefs and bioethical problems, highlights the nature of conferences with family members, and captures several organ procurement issues. The book also includes 30 commonly asked practice problems to resolve diagnostic uncertainties and conflicts along with 12 video clips to assist in neurological evaluation.  






Chapter 1: History of Brain Death


A New Comatose State Appears


Defining Neurologic Criteria for Death in Us





Chapter 2: Neurology of Brain Death


The Pathology of Brain Death


Clinical Examination in Adults


The Clinical Determination of Brain Death in Children


Documentation


Teaching Brain Death Determination


Errors and Alleged Recoveries


Legal Definitions and Obligations





Chapter 3: International Criteria of Brain Death


Guidelines in the United Kingdom


Guidelines World Wide


Consensus for a Uniform World Wide Standard





Chapter 4: Beliefs About Brain Death


Religious Beliefs


Cultural Views


Religious Conflict Resolution





Chapter 5: Critics and Brain Death


The Uncertainty of Death


Emerging Controversies


Critique





Chapter 6: Procurement After Brain Death 


Transitioning to Organ Donation


Organ Procurement Organizations


Organ Donation Requests


Preparation for Determining Organ Suitability


Donation Protocols


Medical Management of the Organ Donor





Chapter 7: Clinical Problems in Brain Death and Organ Donation


1. The Qualifications of the Examiner


2. Clinical Mimics


3. Acid-Base Disturbances


4. Electrolyte Abnormalities


5. Acute Intoxications and Overdose


6. Reliability of Ancillary Tests


7. Ancillary Tests and Confounders


8. Primary Brainstem Lesion


9. Uncertainty About Interpreting Spinal Reflexes


10. Ventilator Autocycling


11. Chronic CO2 Retention and Apnea Test


12. Terminating the Apnea Test


13. Breathing during the Apnea Test


14. Pneumothorax during the Apnea Test


15. Cardiopulmonary Resuscitation


16. Extracorporeal Membrane Oxygenation 


17. Anencephaly 


18. Shaken Baby Syndrome


19. Maternal Brain Death


20. Legal Challenges 


21. Family Opposition 


22. Family Presence during Testing


23. Sperm and Oocyte Retrieval 


24. Organ Donation Management


25. Organ Donation and the Hemodynamically Unstable Donor


26. DCD Pitfalls


27. DCD in the Operating Room


28. Organ Donation in Prisoners


29. Organ Donation, Consent and Costs


30. Organ Donation and Directing the Gift






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